Figure 8
From: Non-canonical Notch signaling represents an ancestral mechanism to regulate neural differentiation
Nvhes2 and Nvhes3 overexpression does not repress NvashA expression. (A-F) Lateral views of embryos expressing NvashA; oral is to the left. There is no discernable difference in NvashA expression in control (A-B), Nvhes2 overexpressing (OE) (C-D), or Nvhes3 (E-F). N >65 scored for each experiment. (G) Relative fold change of NvashA in embryos treated overexpressing Nvhes2 or Nvhes3. (H) Average relative fold change of NvashA, neural genes, and Nvhes genes in animals injected with the NvsuH morpholino (MO; dark grey bars) or a dominant negative NvsuH (DN; light grey bars). Red rectangle denotes relative fold change −1.5 to 1.5, which indicates no change in relative expression. Each injection was repeated three times.