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Fig. 2 | EvoDevo

Fig. 2

From: Feedback circuits are numerous in embryonic gene regulatory networks and offer a stabilizing influence on evolution of those networks

Fig. 2

Classic and updated dGRNs of the endoderm of Sp. On the left is the classic model of the endoderm dGRN using the graphic program BioTapestry [61] (modified after [26]). On the right is an updated version of that GRN with each gene placed along the time line from top to bottom to reflect its time of first expression. Time of first expression is from [37]. Note, when timing is considered, the early specification of endoderm is largely compressed into a 7-h period of the first 24 h of development

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