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Figure 5 | EvoDevo

Figure 5

From: Breaking evolutionary and pleiotropic constraints in mammals: On sloths, manatees and homeotic mutations

Figure 5

Opposing A-P gradients of Retinoic acid (RA), Fgfs and Wnts during early organogenesis influence most processes that take place during this stage, including A-P, Medio-Lateral and Dorso-Ventral patterning of the three germ-layers of the embryo, axial lengthening, cell migration, somitogenesis and the active maintenance of bilateral symmetry of the left and right somites. Modified with permission from [139]

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