Figure 1

Phylogenetic analysis of Glomeris pair rule gene orthologs. (A) Phylograms of orthologs of the Drosophila pair rule genes Even-skipped, Odd-skipped, Odd-paired and Sloppy-paired from various arthropods and the mouse. Closely-related genes from the Drosophila genome serve as outgroups. Un-rooted majority rule consensus trees are shown, computed from 1000 intermediate trees produced with the Quartet Puzzling Method [25]. Reliability values are indicated at the edges. Abbreviations for animals: Cs, Cupiennius salei (spider); Dm, Drosophila melanogaster (fly); Gm, Glomeris marginata (millipede); La, Lithobius atkinsoni (centipede); Mm, Mus musculus (mouse); Sm; Strigamia maritima (centipede); Tribolium castaneum (beetle). Abbreviations for gene names: LMD, Lame duck; SUG, Sugarbabe; BOWL, Brother of odd with entrails limited; CROC, Crocodile; EVE, Even-skipped; EVX, vertebrate Even-skipped ortholog; FKH, Forkhead; FKHBG, Forkhead box G1; ODD, Odd-skipped; ODDR, Odd-skipped-related; OPA, Odd-paired; OPR, Odd-paired-related; PB, Proboscipedia; SLP, Sloppy-paired; SOB, Sister of odd and bowl. (B) Alignment of Runt, Hairy and Paired sequences. Orthologs from Drosophila melanogaster, Tribolium castaneum, Cupiennius salei and mouse are aligned with the available Glomeris marginata gene fragments. Aligned is part of the Runt domain and the C-terminal consensus (for Runt); part of the bHLH domain and the orange domain (for Hairy); part of the Paired domain, the octapeptide and part of the homeodomain (for Paired/Pairberry). Dashes denote identical amino acids, dots indicate gaps introduced to improve the alignment. Question marks stand for missing sequence information. Species abbreviations as in (A). Gene name abbreviations as in (A). Additional abbreviations: DPN, Deadpan; GSB, Gooseberry; GSBN, Gooseberry-neuro; Pax3/7, Pax group III genes; PRD, Paired; H, Hairy; HES, Hairy/Enhancer of split; LZ, Lozenge; PBY, Pairberry; RUN, Runt.