Phylogenetic analysis of Sycon Sox genes based on the HMG domain sequences and schematic representation of motif conservation within groups B, C, E, and F. Maximum likelihood tree using LG + G model of protein evolution is shown. Support values of posterior probabilities (bottom) and bootstrap (top) are displayed, BT values below than 10% and PP values below 0.5 were discarded. A root was placed in the out-groups. P values for Sycon motifs: Group B motif, 9.30E-07; conserved region I, 1.16E-04; conserved region II, 1.99E-05; Group C conserved region, 2.26E-07; Group E conserved region I, 9.03E-10; conserved region II, 4.83E-13; Group F conserved region, 1.40E-14 (SciSoxF1) and 1.10E-10 (SciSoxF2). Ami, Acropora millepora; Amq, Amphimedon queenslandica; Ce, Caenorhabditis elegans; Cin, Ciona intestinalis; Hsa, Homo sapiens; Lco, Leucosolenia complicata; Nv, Nematostella vectensis; Sci, Sycon ciliatum.