Fig. 2
From: Dermestes maculatus: an intermediate-germ beetle model system for evo-devo
Dmac-Prd is similar to Prd from other insects. Alignment of partial Paired (Prd) sequences from D. maculatus, T. castaneum, and D. melanogaster is shown. Black lines indicate the paired domain (PD) and homeodomain (HD). Red arrow indicates S50 in the HD, critical for DNA-binding specificity. The regions used for RNAi experiments are overlined in blue. Protein sequence alignment was performed using ClustalW2. Asterisk indicates identical residues; colon indicates conserved substitutions; full stop indicates weakly similar substitutions. Colors indicate residues classified into groups according to their physicochemical properties. Red Nonpolar side chain; Green Polar side chain; Blue Negatively charged side chain; Magenta Positively charged side chain