Comparative study of Hippo pathway genes in cellular conveyor belts of a ctenophore and a cnidarian

Table 1 Summary of the results of phylogenetic analyses

	Hippo	Salvador	Warts	Mats	Yorkie	Scalloped
Capsaspora owczarzaki	+	–	–	+	+	+
Monosiga brevicollis	+ (*)	+	–	+	+	+
Amphimedon queenslandica	+	– (*)	+	+	+	+
Sycon ciliatum	+	+	+	+	+	+
Trichoplax adhaerens	+	– (*)	+	+	+	+
Pleurobrachia pileus	+	+	+	+	–	+
Mnemiopsis leidyi	+	+	+	+	– (●)	+
Hydra magnipapillata	+	+	+	+	+ (*)	+
Clytia hemisphaerica	+	+	+	+	+	+
Nematostella vectensis	+	+	+	+	+	+
Lottia gigantea	+	+	+	+	+	+
Drosophila melanogaster	+	+	+	+	+	+
Aedes aegypti	+	+	+	+	+	+
Strongylocentrotus purpuratus	+	+	+	+	+	+
Ciona intestinalis	+	+	+	+	+	+
Branchiostoma floridae	+	+	+	+	+	+
Xenopus tropicalis	+	+	+	+	+	+
Danio rerio	+	+	+	+	+	+
Homo sapiens	+	+	+	+	+	+

For each species, the table indicates presence (+) or absence (–) of at least one orthologue for each of six core actors of the Hippo pathway. The symbol (*) indicates discrepancies with previous studies (Yorkie absent in H. magnipapillata and Salvador present in T. adhaerens according to [32]; Hippo absent in M. brevicollis and Salvador present in A. queenslandica according to [34]). (●) Presence of an atypical Yk-like protein in M. leidyi: see text

ISSN: 2041-9139