Fig. 5

Sequence alignment of the C-terminal region of the D. coronatus LET-99 domain in comparison with Caenorhabditis, other nematodes and the homologous mammalian DEPDC1 protein. The C-terminal region is absent in Caenorhabditis species (C. e., C. elegans; C. b., C. briggsae; C. r., C. remanei) but present in the other tested nematodes (D. c., D. coronatus; P. p., Pristionchus pacificus; D. v., Dictyocaulus viviparus; L. l., Loa loa; B. m., Brugia malayi; W. b., Wucheria brancrofti; T. c., Toxocara canis) and vertebrates (O. a., Ornithorhynchus anatinus; M. o., Microtus ochrogaster; T. s., Tarsius syrichta; C. j., Callithrix jacchus; H. s., Homo sapiens)