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Fig. 7 | EvoDevo

Fig. 7

From: Analyses of nervous system patterning genes in the tardigrade Hypsibius exemplaris illuminate the evolution of panarthropod brains

Fig. 7

Phylogenetic and structural analysis of Pax genes. a Phylogenetic analysis of the Pax domain. Maximum likelihood tree topology is shown. Bootstrap support values are shown above select branches (out of 500 replicates) and posterior probabilities are shown below select branches. He-PAX6 is colored tan. He-PAX2/5/8 is colored pink. The names of other sequences from our analysis of H. exemplaris nucleotide data are colored red. b Structure of He-pax6 gene. Relative to the coding strand, 5′ is to the left. Thick lines represent exons. Thin lines represent introns. Black exons represent UTR. Tan exons represent sequences that code for the PAX domain and the homeodomain. Gray exons represent other coding sequences. c Structure of the He-PAX6 protein. d Structure of He-pax2/5/8 gene. The same labeling scheme that is used in panel b is used here, except that the PAX domain is colored pink. e Structure of the He-PAX2/5/8 protein. (b–e) Numbers represent nucleotide or amino acid positions (see Additional file 1: Table S1). An, anonymous sequence (see main text); Dm, Drosophila melanogaster; Ek, Euperipatoides kanangrensis; Er, Euperipatoides rowelli; He, Hypsibius exemplaris; Hs, Homo sapiens

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