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Table 6 Effect of including sex as an interactive versus additive term when modeling the influence of diet on the expression of individual genes

From: Sex-specific plasticity and the nutritional geometry of insulin-signaling gene expression in Drosophila melanogaster

Gene Modela DFb RSSc Fd Pe
InR Tjk = Pj + Pj2 148 100.209   
Tjk = Sk + Pj + Pj2 147 96.398 5.7500 0.0178
Tjk = Sk (Pj + Pj2) 145 96.120 0.2098 0.811
4E-BP Tjk = Sk + Pj 153 52.219   
Tjk = Sk Pj 152 48.604 11.305 0.001
Ash2l Tik = Sk + Ci 152 80.009   
Tik = Sk Ci 151 72.610 15.888 0.0001
Tik = Sk (Ci + Pj + Pj2) 147 68.459 2.229 0.069
CG3071 Tijk = Sk + Ci + Ci2 + Pj + Pj2 123 52.497   
Tijk = Sk (Ci + Ci2 + Pj + Pj2) 118 43.322 4.998 0.0003
dILP2 Tijk = Ci + Ci2 + Pj 123 157.57   
Tijk = Sk + Ci + Ci2 + Pj 122 156.47 0.8623 0.3550
Tijk = Sk (Ci + Ci2 + Pj + CiPj) 119 152.96 0.9097 0.4386
dILP3 Tjk = Pj 152 136.38   
Tjk = Sk + Pj 151 134.35 2.2632 0.1346
Tjk = Sk Pj 150 134.35 < 0.0001 0.9803
dILP5 Tijk = Ci + Pj + Pj2 148 147.40   
Tijk = Sk + Ci + Pj + Pj2 147 142.85 4.6873 0.0320
Tijk = Sk (Ci + Pj + Pj2) 144 139.80 1.0458 0.37431
dILP8 Tjk = Sk + Pj + Pj2 121 205.98   
Tjk = Sk (Pj + Pj2) 119 190.40 4.8693 0.0093
  1. aT is an expression level of gene, S is sex, C is carbohydrate, P is protein. The models differ by having sex as an interactive versus an additive factor. The models chosen are the simplest where one or either sex have significant parameter values
  2. bDegrees of freedom for each model
  3. cResidual sum square
  4. dF-statistic is against model specified in row above
  5. eSignificant P-values are shown in bold