Fig. 5

Zygotic expression onset of tissue-specific effector and specification genes in four representative cell lineages. Zygotic expression onset of tissue-specific effector genes and specification genes are shown in each representative cell lineage: A, B: NSM; C, D: skeletogenic cells; E, F: Veg1/2 endoderm; G, H: apical ectoderm (A, C, E and F: effector genes and B, D, F and H: specification genes). Each dot indicates the timing of expression onset, and dotted lines indicate the timing of cell fate segregation or morphogenesis of a developmental landmark in each cell lineage. Embryonic stages and cell fate segregation are shown in Fig. 1. E egg, Macro/Ma macromere, M micromere, Meso mesomere, Cleav cleavage