Alignment of zinc finger (ZF)-nucleocapsid (NC) and Zic 1-3 odd pared conserved (ZOC) domains. (A) Schematic of Zic protein structure. Relative positions of ZOC, ZF-NC, and 5 ZF domains are shown. (B) Alignment of regions immediately N-terminal to the first cysteine of ZF1 for all Zic proteins that possess ZF-NC-like consensus sequences. (C) Alignment of ZOC-like sequences for Zic proteins that possess a ZOC-like consensus sequence in their amino acid sequence. In both C and D genes identified in this study are in bold.