Phylogenetic relationships, Fezf box, and exon-intron structure of Fezf genes across metazoans. (A) Phylogenetic tree of the putative Fezf orthologs identified in different metazoan genomes generated by Bayesian inference. The orthology of the genes is supported by a posterior probability of 1. (B) Consensus sequence of the conserved Fezf box located near the C-terminal of all bilaterian Fezf orthologs. (C) Alignment of the zinc finger domains of some representative species showing intron positions and intron phases (colored numbers). Only vertebrates and Ciona intestinalis show lineage-specific introns in these domains.