Figure 6
From: Non-canonical Notch signaling represents an ancestral mechanism to regulate neural differentiation
Nvnotch regulates “salt and pepper” differentiation genes. Relative fold change of “salt and pepper” genes in animals following treatment with DAPT (blue bars), injection with Nvnicd (dark orange bars), injection with Nvnicd and NvashA (light orange bars), or NvashA alone (green bars). Red rectangle denotes relative fold change −1.5 to 1.5, which indicates no change in relative expression. “salt and pepper” differentiation genes are suppressed by Nvnotch activity while genes with broad expression domains are unaffected by any of our treatments. OE, overexpressing.