Fig. 5

fgf8 signalling is largely retained in the epithelium throughout (a–c). fgfr1 and fgfr2 are both seen in the epithelium during early denticle morphogenesis (d–i). Expression of dlx2 is restricted to the mesenchyme throughout early placode morphogenesis (j–l). Similarly, bmp4 is observed in the mesenchyme during early placode morphogenesis (m–o). The dashed lines show where in the WMISH the section was taken. WMISH Section 1 represents a younger stage specimen than WMISH Section 2. For the WMISH, D dorsal, V ventral, A anterior and P posterior. For WMISH sections, R right, L left, D dorsal and V ventral. For scale bars, a, b, d, e, g, h, j, k, m, n = 200 µm, ai, bi, di, ei, gi, hi, ji, ki, mi, ni = 100 µm, and c, f, i, l and o = 50 µm