Sex-specific plasticity and the nutritional geometry of insulin-signaling gene expression in Drosophila melanogaster

Table 4 Effect of including sex as an interactive versus additive term when modeling the influence of diet on the expression of multiple genes

Model^a	DF^b	VAR^c	Pillai^d	F^e	P^f
T_ijk = S_k + (C_i + P_j + P_j²)	92	0.53979
T_ijk = S_k (C_i + P_j + P_j²)	89	0.51856	0.5284	2.1254	0.002
T_ijk = S_k (C_i + C_i² + P_j + P_j² + C_iP_j)	85	0.51583	0.3791	1.0599	0.384

^aT is a matrix of expression levels across eight genes, S is sex, C is carbohydrate, P is protein, R is replicate vial (random factor). The models differ by having sex as an interactive versus an additive factor
^bEstimated degrees of freedom for each model
^cGeneralized variance
^dPillai’s trace is against model specified in row above
^eApproximate F-statistic is against model specified in row above
^fP-value for LRT is calculated by parametric bootstrapping using ML fit. Significant P-values are shown in bold

ISSN: 2041-9139