Table 2 Up-regulated genes of interest
Contrast |  |  |  | Log2fold change (transformed mean expression Sample A–Sample B) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Gene model | Type | Classification | Gene | Larvae cf. Whole Adult | Scolex-Neck cf. Mid | Scolex-Neck cf. End | Mid cf. Scolex-Neck | Mid cf. End | End cf. Scolex-Neck | End cf. Mid |
Larvae cf. Whole Adult | ||||||||||
HmN_000064700 | TF | PRD homeobox | aris-like b | 7.4 (160–0) | – | – | – | – | – | – |
HmN_000644000 | TF | TALE homeobox | pknoxb | 6.9 (669–4) | – | – | – | – | – | – |
HmN_000423900 | SC | RTK signalling | FGFR1 | 3.5 (1125–96) | – | – | – | – | – | – |
HmN_000737100 | TF | ETS | elf2-like | 3.3 (131–13) | – | – | – | – | – | – |
HmN_000627700 | TF | HMG-SOX | sox15 | 3.1 (331–37) | – | – | – | – | – | – |
HmN_000595200 | SC | Wnt signalling | fzdEc | 2.7 (1875–282) | – | – | – | – | – | – |
HmN_000680300 | TF | Forkhead box | foxJ3-like | 2.5 (134–22) | – | – | – | – | – | – |
HmN_000892300 | TF | LIM homeobox | lhm3/4 | 2.4 (57–10) | – | – | – | – | – | – |
HmN_000174100 | TF | T-box | tbx2-like | 1.9 (902–249) | – | – | – | – | – | – |
HmN_000112200 | SC | Wnt signalling | wnt2d | 1.8 (166–46) | – | – | – | – | – | – |
HmN_000055700 | SC | Notch signalling | delta-1 | 1.6 (500–168) | – | – | – | – | – | – |
HmN_000089900 | TF | E2F | e2f4-like | 1.3 (1084–432) | – | – | – | – | – | – |
HmN_000599500 | PTR | RNA-binding protein | bruno4-like | 1.1 (2284–1093) | – | – | – | – | – | – |
HmN_000307400 | TF | SINE homeobox | unassignedb | 1.0 (196–96) | – | – | – | – | – | – |
HmN_000446600 | SC | Wnt signalling | dishevelledb | 0.6 (1153–781) | – | – | – | – | – | – |
(Larvae cf. Whole Adult) AND (End cf. Scolex-Neck and Mid) | ||||||||||
HmN_000689300 | SC | RTK signalling | FGFR2 | 3.8 (1797–125) | – | – | – | – | 2.0 (145–36) | 1.7 (159–46) |
HmN_000204900 | TF | Forkhead box | foxO3/4 | 1.2 (3274–1441) | – | – | – | – | 0.8 (1337–758) | 1.2 (1464–634) |
HmN_000191700 | TF | CUT homeobox | cux/CASP-like | 0.6 (1260–843) | – | – | – | – | 0.9 (892–482) | 1.2 (976–414) |
(Larvae cf. Whole Adult) AND (Scolex-Neck cf. Mid and/or End) | ||||||||||
HmN_000125600 | TF | Forkhead box | foxQ2 | 9.0 (866–0.5) | 6.2 (22–0) | – | – | – | – | – |
HmN_000074300 | TF | POU homeobox | pou-like b | 6.8 (100–0) | 4.2 (44–2) | 4.5 (36–0) | – | – | – | – |
HmN_000042400 | TF | PROX homeobox | prox1 | 5.8 (1035–17) | 4.2 (127–7) | 3.4 (105–7) | – | – | – | – |
HmN_000772500 | TF | ANTP-HOXL homeobox | hox4/dfde | 3.8 (1226–91) | 4.7 (1424–53) | 4.5 (1173–47) | – | – | – | – |
HmN_000845400 | TF | PRD homeobox | otp b | 3.7 (157–12) | 3.1 (89–10) | – | – | – | – | – |
HmN_000747700 | TF | POU homeobox | pou4 b | 3.3 (130–13) | 3.4 (58–5) | – | – | – | – | – |
HmN_000874900 | TF | HMG-SOX | soxPF2 | 3.2 (8390–889) | 2.1 (2621–632) | 2.8 (2159–310) | – | – | – | – |
HmN_000639400 | SC | Notch signalling | delta-2 | 3.0 (1697–210) | 3.1 (773–92) | 3.0 (636–75) | – | – | – | – |
HmN_000311000 | TF | Forkhead box | foxD-like | 2.6 (808–136) | 1.4 (279–105) | – | – | – | – | – |
HmN_000553800 | TF | basic Helix-Loop-Helix | myoD | 2.5 (920–158) | 3.2 (909–103) | 3.5 (749–65) | – | – | – | – |
HmN_000227100 | SC | Wnt signalling | fzd1/2/3/6/7b | 2.4 (4783–883) | 1.4 (1616–593) | 1.6 (1331–439) | – | – | – | – |
HmN_000208300 | TF | HMG-SOX | soxPF-1 | 2.2 (1211–260) | – | 1.0 (308–150) | – | – | – | – |
HmN_000521400 | TF | p54 family | p54-like | 1.8 (475–134) | 2.5 (519–91) | 4.1 (427–23) | – | – | – | – |
HmN_000797200 | TF | p53 family | p53-like | 1.8 (2287–640) | 1.1 (714–343) | – | – | – | – | – |
HmN_000676800 | SC | Wnt signalling | strabismus-2b | 1.6 (1810–586) | 0.7 (731–442) | 0.9 (602–326) | – | – | – | – |
HmN_000319700 | SC | Wnt signalling | fzd4/FzBc | 1.6 (2942–994) | 2.1 (3006–687) | 2.2 (2476–530) | – | – | – | – |
HmN_000494900 | TF | HMG-SOX | soxPF-3 | 1.4 (482–185) | 1.9 (680–182) | 2.6 (560–91) | – | – | – | – |
HmN_000049300 | TF | Forkhead box | foxK2-like | 1.3 (830–346) | – | 1.3 (327–133) | – | – | – | – |
HmN_000187500 | TF | ANTP-HOXL homeobox | post2/abdBe | 1.2 (843–355) | 2.1 (1027–233) | 2.1 (846–201) | – | – | – | – |
HmN_000710800 | SC | Notch signalling | groucho2b | 1.0 (4350–2141) | – | 0.9 (1895–1037) | – | – | – | – |
HmN_000853800 | SC | Notch signalling | notch1b | 0.5 (1086–759) | 1.4 (1143–438) | 0.8 (942–537) | – | – | – | – |
Scolex-Neck cf. Mid and/or End | ||||||||||
HmN_000638300 | TF | ANTP-NKL homeobox | emxb | – | 3.6 (97–7) | 3.2 (80–7) | – | – | – | – |
HmN_000385600 | TF | ANTP-HOXL homeobox | meox-1b | – | 3.3 (184–17) | 5.3 (152–2) | – | – | – | – |
HmN_000790000 | TF | Lozenge | lz-2 | – | 2.7 (240–36) | 3.0 (198–24) | – | – | – | – |
HmN_000137200 | TF | bZIP | bZIP137200 | – | 2.3 (1535–312) | – | – | – | – | – |
HmN_000789900 | TF | Lozenge | lz-1 | – | 2.2 (182–39) | 1.8 (150–41) | – | – | – | – |
HmN_000661900 | SC | TGF-β/BMP signalling | bmp2-like | – | 2.2 (87–19) | – | – | – | – | – |
HmN_000146600 | TF | ETS | Fli-1-like | – | 2.2 (48–11) | – | – | – | – | – |
HmN_000068600 | SC | Hedgehog signalling | hedgehogb | – | 1.8 (710–203) | 1.8 (585–163) | – | – | – | – |
HmN_000757800 | TF | POU homeobox | pou3b | – | 1.8 (576–167) | 1.5 (475–168) | – | – | – | – |
HmN_000328000 | SC | Wnt signalling | wnt1d | – | 1.8 (409–119) | 1.4 (337–123) | – | – | – | – |
HmN_000801500 | TF | GATA | GATA2-like | – | 1.5 (194–68) | – | – | – | – | – |
HmN_000737000 | TF | ETS | elf-1-like | – | 1.5 (423–151) | – | – | – | – | – |
HmN_000108100 | SC | Wnt signalling | wnt5d | – | 1.3 (304–120) | – | – | – | – | – |
HmN_000098400 | SC | TGF-β/BMP signalling | noggin-like | – | 1.3 (658–266) | 0.9 (542–280) | – | – | – | – |
HmN_000022800 | SC | Wnt signalling | wnt11bd | – | 1.2 (877–373) | 1.4 (723–267) | – | – | – | – |
HmN_000010800 | TF | Hippo signalling | TEF-5-like | – | 1.2 (854–368) | – | – | – | – | – |
HmN_000071500 | TF | ETS | elf-like | – | 1.2 (453–195) | – | – | – | – | – |
HmN_000359400 | SC | Wnt signalling | sfrp-like/SFLc | – | 0.9 (2930–1523) | – | – | – | – | – |
HmN_000683800 | TF | MADS-box | mef2-like | – | 0.9 (1220–656) | – | – | – | – | – |
HmN_000204800 | TF | CCAAT/EBP | c/ebp-like | – | 0.9 (1321–725) | – | – | – | – | – |
HmN_000762000 | TF | Forkhead box | foxP1-like | – | 0.8 (1182–657) | – | – | – | – | – |
HmN_000395600 | TF | Nuclear receptor | 2DBD-like | – | 0.8 (800–449) | – | – | – | – | – |
HmN_000727700 | SC | TGF-β/BMP signalling | smad4-like-2 | – | 0.8 (435–246) | – | – | – | – | – |
HmN_000031200 | PTR | RNA binding | PA2G4-like | – | 0.5 (4610–3218) | – | – | – | – | – |
HmN_000433400 | TF | Wnt signalling | strabismus-1 | – | – | 2.2 (603–131) | – | – | – | – |
HmN_000204000 | SC | TGF-β/BMP signalling | tgfb-like | – | – | 2.0 (532–129) | – | – | – | – |
HmN_000878900 | SC | TGF-β/BMP signalling | admp-like | – | – | 1.3 (373–152) | – | – | – | – |
HmN_000932100 | SC | Wnt signalling | WIFc | – | – | 1.2 (236–104) | – | – | – | – |
HmN_000997100 | PTR | DEAD-box helicase | unidentified | – | – | 0.9 (791–413) | – | – | – | – |
HmN_000125500 | PTR | Pumilio | pum1 | – | – | 0.8 (1107–634) | – | – | – | – |
Mid cf. Scolex-Neck | ||||||||||
HmN_000727400 | TF | Forkhead box | foxA-like | – | – | – | 8.0 (267–0.9) | – | 7.4 (330–0.8) |  |
HmN_000114300 | PTR | Piwi-like argonaute | group 4 argonautef | – | – | – | 7.2 (5463–31) | – | – | – |
HmN_000666600 | TF | PRD homeobox | otx b | – | – | – | 7.2 (153–0.8) | 2.6 (132–17) | – | – |
HmN_000356000 | TF | TALE homeobox | TALE-likeb | – | – | – | 7.1 (905–6) | – | – | – |
HmN_000762300 | PTR | Boule/DAZL | boule2 | – | – | – | 7.0 (3207–25) | 2.9 (2783–225) | – | – |
HmN_000995400 |  | ubiquitin ligase complex | zyg11-like | – | – | – | 7.0 (1384–11) | – | 6.1 (733–9) | – |
HmN_000832500 | TF | ANTP-NKL homeobox | bsxb | – | – | – | 6.8 (44–0) | – | – | – |
HmN_000607700 | SC | RTK signalling | aFGF-like-2 | – | – | – | 6.4 (372–4) | – | – | – |
HmN_000466300 | TF | PRD homeobox | pax4/6b | – | – | – | 6.3 (50–0.3) | – | – | – |
HmN_000018500 | SC | RTK signalling | aFGF-like-2 | – | – | – | 6.2 (331–4) | – | – | – |
HmN_000400200 | TF | ANTP-HOXL homeobox | post2-likee | – | – | – | 6.0 (155–3) | – | – | – |
HmN_000720400 | TF | TALE homeobox | TALE-like-2b | – | – | – | 6.0 (470–7) | 3.0 (407–38) | – | – |
HmN_000625100 | TF | RFX winged-helix DBD | rfx3-like | – | – | – | 5.9 (268–4) | 2.5 (233–32) | – | – |
HmN_000469100 | TF | TALE homeobox | meis-like | – | – | – | 5.6 (507–9) | – | – | – |
HmN_000199100 | TF | PRD homeobox | pax-like | – | – | – | 4.7 (141–6) | 1.8 (122–33) | – | – |
HmN_000194800 | TF | ANTP-NKL homeobox | dlxb | – | – | – | 4.6 (1422–59) | – | – | – |
HmN_000016500 | TF | ANTP-NKL homeobox | msxlx b | – | – | – | 4.4 (1037–48) | – | – | – |
HmN_000453400 | TF | ANTP-HOXL homeobox | meox-3b | – | – | – | 4.0 (27–1) | – | – | – |
HmN_000142300 | TF | Forkhead box | foxC-like | – | – | – | 3.9 (144–9) | – | – | – |
HmN_000582900 | TF | LIM homeobox | lhx2/9b | – | – | – | 3.6 (163–13) | 2.9 (141–15) | – | – |
HmN_000304300 | TF | CUT homeobox | onecut | – | – | – | 3.3 (1359–135) | – | – | – |
HmN_000307900 | PTR | DEAD-box helicase | ddx17-like | – | – | – | 3.3 (75–7) | – | – | – |
HmN_000525500 | TF | DM domain sex-determining | dmrt-like | – | – | – | 2.9 (114–15) | – | – | – |
HmN_000961600 | TF | PROX homeobox | prox-2 | – | – | – | 2.7 (460–69) | – | 3.3 (589–57) | – |
HmN_000385900 | TF | E-box | E2-alpha-like | – | – | – | 2.4 (1681–321) | – | – | – |
HmN_000343800 | TF | basic Helix-Loop-Helix | HES2b | – | – | – | 2.4 (130–25) | – | – | – |
HmN_000631100 | TF | B cell factor family | ebf/coe-like | – | – | – | 2.3 (135–27) | – | – | – |
HmN_000621400 | TF | C2H2 zinc finger homeobox | zfh-1 | – | – | – | 1.9 (795–216) | – | – | – |
HmN_000875600 | TF | Forkhead box | foxJ1-like | – | – | – | 1.7 (1116–341) | 2.3 (967–176) | – | – |
HmN_000516200 | PTR | Pumilio | pum2 | – | – | – | 1.4 (1969–757) | – | – | – |
HmN_000467100 | TF | X-box | nfx1-like | – | – | – | 1.0 (1295–641) | – | – | – |
HmN_000663500 | TF | ANTP-NKL homeobox | nk5/hmxb | – | – | – | 1.0 (1102–563) | – | – | – |
HmN_000278200 | TF | Basic leucine zipper | bZIP278200 | – | – | – | 0.9 (294–155) | – | – | – |
HmN_000190500 | TF | ANTP-NKL homeobox | nk6b | – | – | – | 0.8 (944–541) | – | – | – |
HmN_000629700 | TF | Notch signalling | strawberry notchb | – | – | – | 0.7 (1317–819) | – | – | – |
(Mid cf. End) AND (End cf. Scolex-Neck) | ||||||||||
HmN_000458100 |  | ubiquitin ligase complex | zyg-11-like | – | – | – | – | 2.2 (793–164) | 1.6 (150–47) | – |
End cf. Scolex-Neck and/or Mid | ||||||||||
HmN_000663000 | TF | HMG-Sox | sox5/6 | – | – | – | – | – | 3.1 (639–71) | – |
HmN_000117000 | TF | ANTP-NKL homeobox | barh-likeb | – | – | – | – | – | 1.6 (627–202) | 1.1 (685–312) |
HmN_000560200 | TF | basic Helix-Loop-Helix | bigmax-like | – | – | – | – | – | 1.4 (2059–781) | 1.1 (2251–1019) |
HmN_000337700 | SC | Slit-Robo signalling | slit-like | – | – | – | – | – | 1.3 (984–393) | – |
HmN_000208700 | TF | ANTP-NKL homeobox | nk2.1b | – | – | – | – | – | 1.1 (1107–511) | 0.8 (1210–684) |
HmN_000354400 | SC | Wnt signalling | GSK3-like | – | – | – | – | – | 0.9 (1823–935) | – |
HmN_000758500 | PTR | Pumilio | pum3 | – | – | – | – | – | 0.8 (4341–2460) | 0.8 (4742–2621) |
HmN_000556500 | SC | Wnt signalling | sfrpc | – | – | – | – | – | 0.7 (751–449) | 1.1 (823–391) |
HmN_000215100 | TF | Basic leucine zipper | bzip-574300 | – | – | – | – | – | – | 1.8 (493–132) |
HmN_000727600 | SC | TGF-β/BMP signalling | smad4-like-1 | – | – | – | – | – | – | 0.8 (775–429) |